senile plaques
英 [ˈsiːnaɪl plɑːks]
美 [ˈsiːnaɪl plæks]
网络 老年斑; 的老年斑; 衰老斑; 老人斑; 老化斑
双语例句
- Firstly, a modified fuzzy C means method is used on the RGB color space to identify senile plaques and neurofibrillary tangles in microscopic image of the hippocampus separately.
利用改进的模糊C均值算法对彩色图像的颜色信息进行聚类，分别提取了老年斑和神经元纤维缠结目标。 - Segmentation of senile plaques and neurofibrillary tangles is crucial to pathological analysis of Alzheimer's disease.
老年斑和神经元缠结的分割提取对于阿尔茨海默症病理研究有重要的意义。 - The characteristic microscopic findings of Alzheimer's disease include "senile plaques" which are collections of degenerative presynaptic endings along with astrocytes and microglia.
Alzheimer病典型的显微镜表现包括“老年斑”与星形胶质细胞和小胶质细胞，老年斑是变性的突触前末梢。 - Senile plaques: All referred to as "senile pigment spot," also known as medical seborrheic.
老年斑：全称为“老年性色素斑”，医学上又被称为脂溢性角化。 - Objective To investigate the distribution of free zinc ions and β-amyloid precursor protein ( APP) in the senile plaques of an Alzheimers diseased animal model, the APP/ PS1 transgenic mouse.
目的研究阿尔茨海默病（AD）动物模型-APP/PS1转基因鼠大脑内游离锌离子和β淀粉样蛋白前体蛋白（APP）在老年斑内的分布。 - Results A new neuropathological change-"axonal leakage" in the brains of AD patients was identified, which was accompanied by swellings of varicosities and axons, and was related to the degree of senile plaques and neurofibrillary tangles.
结果AD患者脑出现重要的神经病理改变轴突漏（axonalleakage）。轴突漏常伴随肿胀的轴突和轴突膨体，且与传统的神经病理改变斑块和神经原纤维缠结有明显的相关性。 - Objective To study the effect of GM1 ganglioside interfering the metabolism of amyloid β protein precursor ( APP) on cells for exploring the relationship between GM1 and development of Alzheimer senile plaques and the other amyloidoses.
目的研究外源性神经节苷脂GM1干扰细胞β－淀粉样蛋白前体代谢的作用，探讨GM1与阿尔采默病特征性病理变化老年斑和其他淀粉样病变形成的关系。 - Objective The combination of the antibodies which induced by subunit vaccine of A β_ ( 42) with senile plaques in the hippocampus of patients with Alzheimer disease was observed to screen the subunit vaccine of A β_ ( 42).
目的观察Aβ42亚单位肽疫苗接种SD大鼠产生的抗体与阿尔茨海默（Alzheimer）病人脑海马老年斑结合的情况，以筛选A4β2亚单位片段。 - From 2002 to 2004 senile plaques were selected from hippocampus of 6 patients with senile dementia, including 3 males and 3 females, aged from 60-81 years, in Geriatrics Institutes, Affiliated Hospital of Anhui Medical University. Delay time after death was shorter than 8 hours.
于2002/2004在安徽医科大学附属医院老年病研究所采用老年性痴呆症海马6例，男3例，女3例，年龄60～81岁，死亡耽搁时间小于8h。 - Its main neuropathological features include diffuse loss of neurons in the hippocampus and neocortex, neurofibrillary tangles, accumulation of extracellular amyloid or senile plaques.
AD的神经病理表现主要是海马区和新皮质区弥散性的神经元丢失、神经纤维缠结和细胞外的类淀粉样沉积。 - Lipofuscin is called aged pigment, it can deposit on the skin of the elderly ceaselessly and form senile speckles or senile plaques.
脂褐素是一种老年性色素，它能沉积于皮肤表面形成老年斑。 - The long amyloid β Protein(β A4 42) is a major constituent of the senile plaques in Alzheimer's disease.
与短β┐淀粉样蛋白（βA440）比较，长β┐淀粉样蛋白（βA442）在Alzheimer病老年斑生成中具有更重要的作用。 - Characteristics of senile plaques in the hippocampus of patients with senile dementia and transgenic mice
老年性痴呆症患者及转基因小鼠模型海马部位老年斑的特征 - RESULTS: Senile plaques, neurofibrillary tangles and neuronal death, in which free radicals are all involved, represent the three pathological features of Alzheimer disease. Therefore, the application of ectogenous antioxidant is a potential method for the drug treatment of Alzheimer disease.
结果：阿尔茨海默病3种主要病理变化-老年斑、神经纤维缠结、神经元死亡都有自由基参与，因此外源性抗氧化剂的应用是阿尔茨海默病药物治疗的有前途的一种方法。 - Cerebral Ischemia and Senile Plaques in Alzheimer's Disease
脑缺血与Alzheimer病的老年斑 - Amyloid beta protein ( AP), the major ingredient of senile plaques, plays a critical role in the development of AD.
构成老年斑的主要成分β-淀粉样蛋白（Amyloidbetaprotein，Aβ）在AD发病过程中起重要作用； - Aggregation of Amyloid beta-protein ( A β) in senile plaques is related to the pathogenesis of AD, so it is very important for the studies on the prevention of A β deposition and on trying to disaggregate the senile plaques, aimed at treatment and prevention of the AD.
β淀粉样蛋白（Aβ）在老年斑中的积聚与AD发病关系密切。因此，如何抑制老年斑内Aβ的积聚和促进Aβ纤维的解聚对于治疗和预防AD有十分重要的意义。 - The CAA was often accompanied with the senile plaques and neurofibrillary tangles.
CAA往往同时伴有老年斑和神经原纤维缠结。 - The expression of calcium/ calmodulin-dependent protein kinase ⅱ in the senile plaques in Alzheimer disease
钙/钙调素依赖的蛋白激酶Ⅱ-α在Alzheimer病老年斑的表达 - OBJECTIVE: Alzheimer's disease is characterized by the formation of two main protein aggregates: senile plaques and neurofibrillary tangles, which are involved in the process leading to progressive neuronal degeneration and death.
目的：阿尔茨海默病的两大病理特征是老年斑与神经原纤维缠结，这两种病变可导致渐进的神经元变性并与神经元死亡有关。 - Objectives To investigate the neurotoxicity of beta amyloid ( A β) consisting of senile plaques in Alzheimer disease ( AD) in the animal model.
目的探讨β淀粉样蛋白（Aβ）海马内注射的神经毒性，并对应用此方法建立阿尔茨海默病（AD）的动物模型进行初步评价。 - Results CR2 was detected in senile plaques and neurofibrillary tangles of the hippocampus and the temporal isocortex in AD brain tissues.
结果AD患者海马、颞叶脑组织中的特异性病变组织老年斑和神经纤维缠结有CR2表达。（2）神经纤维缠结； - In Non-gmo models most only simulate a certain aspect of AD pathology characteristics, while the pathological process of AD is complex, various, and do not present the AD typical characteristic in the brain: senile plaques ( SP) and neurofibrillary tangles ( NFTs).
非转基因模型中，大部分模型只针对AD病理特征的某一个方面，而AD的病理过程是复杂的多方面的，且不呈现AD脑内特征性改变：SP和NFTs。 - Chronic stress and glucocorticoids exposure may also lead to generation and deposition of A β and formation of senile plaques in brain tissue of transgenic AD mice.
研究发现慢性应激和外源性糖皮质激素暴露均可导致转基因AD模型小鼠脑组织Aβ生成增加，促进Aβ沉积和老年斑的形成。 - Hippocampal ( hippocampus, dentate gyrus) have part of the nerve cell nucleus condensation and degeneration, white matter loose edema, and a large number of senile plaques formed.
海马结构（海马、齿状回）部分神经细胞核固缩、变性伴胶质细胞增生，白质疏松水肿，大量老年斑形成。 - Application Thioflavin S staining and immunohistochemistry to analysis the number and area of the senile plaques in the mouse brain slices.
用硫磺素硫及免疫组化的方法，观察小鼠脑片老年斑沉积的数量及面积。 - Some scholars believe that c1q plays a toxic effect in AD: c1q can combine with A beta peptide and promote the nucleation process of senile plaques.
部分学者认为clq在AD发病中起着毒性作用：clq通过与Ap多价结合，促进老年斑的成核过程。